The Phenylpropionate ester is a moderately small or short ester, possessing a half-life far shorter than longer esters such as Enanthate or Cypionate but larger and longer than esters such as Propionate. To give a point of reference, Nandrolone-Decanoate will carry with it a half-life of approximately fifteen days while the Phenylpropionate form of nandrolone will only possess a half-life of approximately 96-120 hours. For this reason, steroids with the Phenylpropionate ester attached will need to be administered more frequently than longer ester based steroids such as Decanoate or Enanthate. Most Durabolin users, as this is the most common Phenylpropionate based steroid will find injections every three days to be the minimal time frame while every 48 hours will prove to be far more efficient.
Metabolic effects occurring during anabolic steroid therapy in immobilized patients or those with metastatic breast disease have included osteolytic-induced hypercalcemia. Anabolic steroids affect electrolyte balance, nitrogen retention, and urinary calcium excretion. Edema, with and without congestive heart failure, has occurred. Decreased glucose tolerance requiring adjustments in hyperglycemic control has been noted in diabetic patients. Significant increases in low density lipoproteins (LDL) and decreases in high density lipoproteins (HDL) have occurred. [ Ref ]