Research shows little evidence of abnormal or unhealthy psychological changes in men receiving supervised testosterone therapy to treat their low T, according to a study in the journal Therapeutics and Clinical Risk Management. However, mental and physical risks are involved in self-administration of artificial testosterone. Anyone abusing synthetic testosterone, also known as anabolic steroids, may experience episodes of aggressive or violent behavior, along with physical side effects. Bodybuilders, athletes, or anyone who seeks to build muscle mass or achieve other benefits from artificial testosterone should be aware of these risks.
Other side effects include increased risk of heart problems in older men with poor mobility, according to a 2009 study at Boston Medical Center. A 2017 study published in JAMA found that treatments increase coronary artery plaque volume. Additionally, the Food and Drug Administration (FDA) requires manufactures to include a notice on the labeling that states taking testosterone treatments can lead to possible increased risk of heart attacks and strokes. The FDA recommends that patients using testosterone should seek medical attention right away if they have these symptoms:
4. Through a complex process that I’m not even going to attempt to describe, our testicles’ Leydig cells convert cholesterol into testosterone. That’s right, cholesterol is the building block of testosterone. Leydig cells get most of what they need to produce T by simply absorbing the cholesterol floating around in our blood from the bacon and eggs we ate in the morning. If there’s not enough cholesterol in our blood, our testicles can produce a bit of it so that the Leydig cells can convert it to testosterone. But relying too much on cholesterol produced by our nuts (of the non-almond variety) can actually inhibit our Leydig cells from producing T . You gotta eat those eggs!